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Transient macular edema after intracameral injection of a standard dose of cefuroxime during phacoemulsification surgery: a report of three cases

Poster Details

First Author: A.Saitta ITALY

Co Author(s):    L. Avoni   A. Bratu   P. Rossini   A. Volinia   D. D'Eliseo        

Abstract Details


Macular edema and detachment at the first day after an uneventful cataract surgery is very rare, and has been reported previously with the use of high concentrations of intra-cameral cefuroxime. However, we hereby reported three cases of macular edema with extensive serous retinal detachment the first day after an uneventful phacoemulsification with intra-cameral injection of a standard dose of cefuroxime during the procedure.


Department of Ophthalmology, 'Santa Maria delle Croci' Hospital, Ravenna, Italy


Three eyes of three patients without any preexisting ocular comorbidity underwent an uneventful phacoemulsification surgery and 1 mg/0.1 ml of cefuroxime solution was injected into the anterior chamber at the end of the procedure. Combination of nonsteroidal anti-inflammatory drugs and corticosteroids was applied in all cases topically as routine anti-inflammation treatment after phacoemulsification.


Visual dysfunction secondary to macular edema with extensive serous retinal detachment around macula and optic disc area was observed the first day after surgery in all cases. Without surgical intervention, a quick recovery of the macular edema and retinal detachment was observed by spectral domain optical coherence tomography 1 week later (range 3-10 days) in all cases. Visual recovery was complete. No recurrence of macular edema or retinal detachment was noticed until the last follow-up (6 months after surgery).


We presumed that intracameral injection of cefuroxime sodium at a standard dose of 1 mg/0.1 mL may be associated with transient macular edema and diminished visual acuity, resolving largely within 1 week. Routine anti-inflammatory treatment is sufficient and do not require excessive interventions.

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