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Nanodrops for restoring refractive errors

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Session Details

Session Title: Presented Poster Session: Keratorefractive Results II

Venue: Poster Village: Pod 2

First Author: : D.Smadja ISRAEL

Co Author(s): :    J. Lellouche   R. Ishay Ben   Y. Harel   Z. Zalevsky     

Abstract Details


To investigate the capacity of eyes drops filled with a solution of nanoparticules with particular optical properties to correct various range of refractive errors


Institute of Nanotechnology and Advances Materials Bar-Ilan University, Tel Aviv Israel


Experimental study analyzing the refractive errors of 10 pig eyes measured with an automated refractometer before and after instillation of eye drops filled with various concentration of synthetic nanoparticules. The magnitude of the refractive change, the corneal refractive index, and the corneal shape modification have been recorded as well as an electronic microscopic exam in order to identify the nanoparticules inside the cornea.


A mean correction of 2,24 +/- 0.07D has been achieved for myopic refractive error testing, whereas a correction of 1,96+/-0.2D has been achieved for hyperopic refractive error. No statistically significant changes have been observed in the corneal central keratometry. Encapsulated hypereflective nanoparticules of 0.58nm diameter on average were observed throughout the first 60microns of the corneal thickness.


Eyes drops filled with synthetic nanoparticules have shown promising potential for a revolutionary alternative non-invasive correction of refractive errors.

Financial Disclosure:

has significant investment interest in a company producing, developing or supplying product or procedure presented

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