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Biomechanical characterization of subclinical keratoconus without topographic or tomographic abnormalities

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Session Details

Session Title: Presented Poster Session: Cornea III

Venue: Poster Village: Pod 2

First Author: : R.Vinciguerra ITALY

Co Author(s): :    R. Ambrosio   C. Roberts   C. Azzolini   P. Vinciguerra     

Abstract Details


To present a case series of patients with subclinical keratoconus diagnosis with normal topometric (anterior curvature) and tomographic findings who showed abnormalities detected by Corvis ST in-vivo biomechanical assessment.


Vincieye Clinic, Milan, Italy


All patients had a complete ophthalmic examination, including the Corvis-ST biomechanical measuremements, optical tomography and pachymetry with Pentacam (OCULUS Germany) and placido based topography either with the Nidek (OPD III Nidek, Japan) or CSO platform(C.S.O.,Florence, Italy).The inclusion criteria of this study included to have a clinical diagnosis of ectasia in one eye and the fellow eye to have normal topometric and tomographic findings (Subclinical Keratoconus),including a Belin/Ambrósio Enhanced Ectasia total deviation index(BAD-D)from the Pentacam with less than 1.6 standard deviations (SD) from normative values.The second inclusion criterion was a Corvis Biomechanical Index(CBI)of more than 0.5 in both eyes.


We report a case series of twelve patients with tomographic and topographic analysis, which was normal in one eye and abnormal in the fellow eye. In all presented patients, the biomechanical results with the CBI were shown to be abnormal in both eyes and aided the diagnosis.


In conclusion this report showed that biomechanical analysis showed abnormalities while tomography and topography were normal. Basing on these findings we suggest the use of biomechanics as an additional diagnostic tool.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a competing company

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