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Corneal collagen crosslinking after intrastromal corneal ring segment implantation in keratoconus

Poster Details

First Author: O.Ucakhan TURKEY

Co Author(s):    B. Bayraktutar              

Abstract Details


To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) following INTACS implantation in progressive keratoconus.


Department of Ophthalmology, Ankara University School of Medicine, Ankara, Turkey


Twenty progressive keratoconus patients (31 eyes) with contact lens intolerance were included into this prospective study. All patients had INTACS implantation followed by standard CXL. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, slit-lamp examination, corneal topography, central corneal thickness (CCT), endothelial cell counts were noted before and after INTACS implantation and at months-1,3,6 and 12.


The mean age of the patients was 27.8 ± 6.1(20-43) years. The mean interval between INTACS implantation and CXL was 3.9 ± 4.1 months. The mean follow-up after the last surgery (CXL) was 15.1 ± 8.9 months. Following INTACS implantation, UDVA and CDVA improved 2 Snellen and 1 Snellen line, respectively. The mean manifest refraction spheric equivalant decreased 2.4±0.5 D and the mean keratometry readings flattened by 1.5±0.5D (p<0.05). Refractive and topographic findings remained stable throughout the follow-up period. No endothelial cell loss was or intra- or post-operative complications were encountered in any patient eye.


Combined INTACS and CXL seems to be safe and effective for the correction of refractive error and halting the progression of disease in selected patients with keratoconus.

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