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Magnetic resonance tractography in patients with retrobulbar neuritis

Poster Details

First Author: G.Khamraeva UZBEKISTAN

Co Author(s):    H. Kamilov   M. Kasimova           

Abstract Details


The aim of this study was to investigate informativeness of the MR-tractography in patients with retrobulbar neuritis.


Uzbekistan, Tashkent, Tashkent Institute of Postgraduate Medical Education


The study involved 32 people aged 18 to 55 years. Of them are 18 women, 14 men. 10 volunteers appropriate age category without ophthalmic pathology average compose the control group (group 1). 22 patients had a diagnosis of retrobulbar neuritis (2-group).Tractography was performed on magnetic - resonance imaging to the field strength of 1.5 Tesla GE (BRIVO-355/USA). Number of slices - 96. Slice thickness - 2.3 mm gap between them - 0, the image field - 220 mm, repetition time - 6,599-8,280 ms, echo time - 70 ms, the diffusion coefficient - 600 s/mm2. Research time about 9 minutes.


MR tractography at normal levels observed in healthy control group. In 22 patients of the group 2 observed the following changes: thinning fibers large occipital forceps - 6 patients, a partial tear of the upper row of fibers in place of attachment to the optic radiation beam - at 4, partial visualization medial fibers of the optic beam - at 5, their intermittency - at 3, thinning of lateral right optic fiber beam - at 2, their differentiation in small amounts observed in 2 patients.


Revealed changes as a thinning of nerve fiber optic radiation with partial interruption of nerve fibers suggesting that the inflammatory process affects not only the third neuron, but may be accompanied by a fourth neuron lesion, which requires a comprehensive approach to therapy.

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