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The use of novel corneal index in the diagnosis of keratoconus

Poster Details

First Author: F.Orucoglu TURKEY

Co Author(s):                  

Abstract Details


To evaluate the use of new index in diagnosing keratoconus (KC)


Birinci Eye Hospital, Istanbul


The new fromula aims to combine keratoconus indices with posterior corneal shape and corneal thickness. In the formula of OI=[(SKI+BE)x(1-BQ)]/TCT; OI,SKI, BE, BQ and TCT respectively stands for, Orucoglu Index, Sum of Keratoconus Indices (ISV,IVA,KI,CKI,IHA,IHD), Back Elevation in thinnest location, back corneal asphericity and Thinnest Corneal Thickness. OI formula is assessed by the receiver operating characteristic (ROC) curve analysis for the measurement of its usefulness in discriminating between KC eyes and normal control eyes.


Avarage OI value was 0.058±0.02 (Range from 0.02 to 0.13) in normal eyes and 0.504±0.44(Range from 0.09 to 4.22) in keratoconus eyes (p<0.001). Receiver operating characteristic curve analyses showed the excellent predictive accuracy for OI (ROC 0.998(95% CI:0.997-0.999). The OI distinguished the keratoconus group from the normal group with 97% sensitivity and 99% specificity at the best cut-off point of 0.12.


The index is based on information not only the anterior corneal surface but also the posterior corneal surface and corneal thickness. In our pilot study, OI showed excellent accuracy, sensitivity, and specificity in the diagnosis of KC.

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