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Surgically induced corneal astigmatism following intravitreal ranibzumab injection

Poster Details

First Author: T.Kocaturk TURKEY

Co Author(s):    E. Erkan   S. Egrilmez   H. Cakmak   S. Dundar   V. Dayanir  

Abstract Details


To evaluate surgically induced astigmatism after an intravitreal ranibizumab injection in patients with wet-form age-related macular degeneration, diabetic macular edema and branch vein occlusions.


58 patients who had received IVR injections in the Department of Ophthalmology, Adnan Menderes University School of Medicine have been researched and corneal topographic values including K1, K2, axis and IOP levels were noted from patients’ postoperative follow-ups.


The eyes of 58 patients were included in this study. Patients’ pre- and postoperative detailed ophthalmologic examinations were done; intraocular pressures and topographic keratometric values (K1, K2) were noted from their follow-ups. The outcome measures in the study were statistically compared according to IOP and surgically induced astigmatism.


The mean preoperative absolute astigmatism of 0.87D was 0.95 Diopters (D) on the 1st day; 0.75D on the 3rd day; 0.82D in the 1st week; and 0.78D in the 1st month. The absolute change in astigmatism was 0.08D on the 1st day, 0.12D on the 3rd day, 0.05D in the 1st week and 0.09D in the 1st month. When we performed a vectorial analysis the mean value of induced astigmatism were found to be 0.33±0.22D on the 1st day, 0.32±0.29D on the 3rd day, 0.41±0.37D in the 1st week and 0.46±0.32D in the 1st month.


The absolute change in astigmatism seem to be insignificant in terms of refractive analysis. However, when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, we found measurable differance vectorially in SIA. Our results suggest that, although intravitreal injection is a minimally invasive ophthalmologic procedure, it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.

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