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Evaluation of intraocular pressure in penetrating keratoplasty

Poster Details

First Author: A.Cabugueira PORTUGAL

Co Author(s):    V. Lemos   A. Vicente   R. Flores   T. Gomes   F. Fernandes   M. Reina

Abstract Details


The authors aim to evaluate the intraocular pressure (IOP) before and after penetrating keratoplasty (PK).


Several complications can occur after PK. Glaucoma is one of most important complications because it could cause optic disc damage and graft failure.


Retrospective, nonrandomized study. Evaluated 170 eyes followed in Corneal Department of a tertiary hospital, who underwent PK in the context of several pathologies. Past medical and ocular history, visual acuity and IOP before and after surgery (one week, one month, three months, six months and one year) were registered. The sample was divided into two groups according to the diagnosis of glaucoma before surgery.


Mean age of 61.21±19.2 years, 52.4% male subjects and 24.1% had glaucoma. The indications for PK were: bullous keratopathy (37.1%), keratoconus (24.7%), nonspecific opacity (23.5%), infected ulcer (4.7%), Fuchs dystrophy (4.7%) and perforation (2.9%). When comparing IOP between glaucoma group and group without glaucoma, before PK (18.90mmHg±5.58 vs. 14.61±3.23), first week (17 vs. 22.79±9.46 vs. 54±1.04), three months (21.72±8.26 vs. 17.27±6.40) and six months (20.44±6.98 vs. 16.78±4.91), there was statistically significant difference. However, one year after surgery the difference between groups is not statistically significant (19.41±4.93 vs. 18.80±6.37; p=0.6).


Several factors must be considered for PK. Presence of glaucomatous optic neuropathy should be considered, because these patients are more prone to increased IOP and may cause graft failure. Regular monitoring of IOP is essential, allowing the identification of its rise and establishment of appropriate early treatment.

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