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Corneal involvement in Triple A syndrome : A case report.

Poster Details

First Author: N.Abroug TUNISIA

Co Author(s):    R. Kahloun   I. Ksiaa   A. Mahmoud   B. Jelliti   S. Ben Yahia   M. Khairallah

Abstract Details


To describe ophthalmic features of triple A syndrome (Allgrove syndrome).


Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia


A 27-year-old female, diagnosed with triple A syndrome, was referred to our department for ophthalmic evaluation. On ocular examination, her best-corrected visual acuity was 20/400 in both eyes with constant esotropia of the right eye. Refraction showed important astigmatism. Slit-lamp examination revealed severe keratoconjunctivitis sicca with corneal opacities and mild superficial punctate keratopathy. Results of fundus examination were normal in both eyes. The patient was treated with topical tear substitutes.


Triple A syndrome is a rare, autosomal recessive disorder characterized by adrenal insufficiency, alacrima and achalasia. Alacrima is the first and most consistent feature of this syndrome. Ophthalmologist should be aware of this rare disorder and look for systemic features in patients with ophthalmic manifestations of dry eye.



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