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Corneal intraepithelial neoplasia first misdiagnosed as a keratitis: A case report

Poster Details

First Author: N.Abroug TUNISIA

Co Author(s):    R. Kahloun   A. Bouaban   J. Nemria   B. Jelliti   S. Zaouali   M. Khairallah

Abstract Details


To describe the clinical findings in a patient who was initially diagnosed with and treated for keratitis, and who was finally diagnosed with corneal intraepthelial neoplasia.


Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia


A 66-years-old male was referred for decreased vision in the left eye. He had a history of previous episodes of keratitis treated several times without improvement. Best- corrected visual acuity was 20/20 in the right eye and 60/200 in the left eye. Slit-lamp examination of the left eye revealed a geographic, gray, translucent, and well- demarcated lesion strictly limited to the epithelium. No associated stromal abnormalities were seen. Ocular examination results of the right eye were unremarkable. Corneal scrapping with histopathologic examination of the removed tissue disclosed intraepithelial neoplasia. The patient underwent corneal epithelial debridement. Post-operative treatment with topical mitomycine C and Ciclosporine A was prescribed, resulting in a complete resolution of the corneal lesion.


Intraepithelial neoplasia are the main primary tumors of the cornea. They are rare and characterized by a slow progression. Ophthalmologist should be aware of this disorder to ovoid misdiagnosis with other corneal pathologies.



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