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Posterior capsule opacification rates of the Rayner Superflex and the Alcon Acrysof SA60AT Intraocular Lenses

Poster Details

First Author: M.Weber AUSTRIA

Co Author(s):    N. Hirnschall   V. Ashok   V. Gangwani   Y. Nishi   V. Maurino   O. Findl

Abstract Details


To compare the posterior capsule opacification rates and the lens epithelial cell (LEC) migration across the optic edge and optic-haptic junctions of two different Intraocular lenses (IOLs): the Superflex (Rayner) and the Acrysof SA60AT (Alcon).


Moorfields Eye Hospital, London; Department of Ophthalmology, Scarborough Hospital, Scarborough; Vienna Institute for Research in Ocular Surgery, Department of Ophthalmology, Hanusch Hospital, Vienna


This prospective multicentre study included patients who were scheduled for bilateral cataract surgery. Randomly, one eye received the hydrophilic Superflex IOL with a 360° barrier and 6.25mm optic diamter (Superflex group) and the other eye the hydrophobic Acrysof IOL with an optic diameter of 6 mm (Acrysof group). Purpose of the study was to compare the LEC migration across the optic edge and the optic-haptic junctions as well as the posterior capsule opacification assessed with an automated quantification system (AQUA) over a period of two years using serial high resolution retroillumination digital photographs.


In this study 60 eyes of 30 patients were included. Capsule performance was found to be similar between both IOLs and no significant difference was found for anterior capsule opacification, or post-operative capsule IOL contact. Two years after surgery the AQUA score was 1.59 (SD: 1.75) and 2.04 (SD: 1.60) in the Superflex and Acrysof groups, respectively (p=0.52).


Although differences were not found to be significant, there was a trend that the IOL with the larger optic (Superflex) had slightly reduced PCO rates. Otherwise, the performance of both IOLs was similar.

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