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Correlation of microperimetry measurements with cataract grading

Poster Details

First Author: D.Liakopoulos GREECE

Co Author(s):    A. Pallikaris   M. Tsilimbaris   G. Kymionis   I. Pallikaris     

Abstract Details


To evaluate macular light sensitivity and fixation stability measured with microperimetry in patients with age related cataract before and after phacoemulsification cataract surgery, and to correlate them with cataract grading.


University Hospital of Crete, Heraklion, Crete, Greece


In this prospective, interventional study, thirty (30) eyes of 28 patients (17 male, 11 female, age 71.47±5.74) undergone phacoemulsification cataract surgery followed by implantation with monofocal IOL were recruited. Main exclusion criteria were the presence of any retinal pathology. A comprehensive ophthalmological examination was performed preoperatively, 15 and 30 days postoperatively, including best corrected distance visual acuity (BCVA) using logMAR EDTRS chart. Preoperative cataract grading was based on the images of the Lens Opacities Classification System (LOCS III). Average threshold sensitivity (ATS) and fixation stability was evaluated at all time intervals using the microperimeter MAIA (Centervue Inc., Padova, Italy).


Preoperative BCVA and ATS was 0.39±0.20 logMAR and 23.77±3.37 dB, respectively, and statistically improved at 15 (0.10±0.10 logMAR, and 27.69±1.95 dB, p=0.001), and 30 days (0.04±0.06 logMAR and 28.96±1.89 dB, p=0.001) postoperatively. BCVA and ATS significantly correlated at all time intervals (p=0.001). Posterior subcapsular cataract (PSC) significantly correlated with the improvement in BCVA at 2 and 4 weeks (r=0.465, p=0.010; r=0.599, p=0.001). PSC and nuclear opalescence (NO) statistically correlated with the improvement in ATS at 4 weeks (r=0.403, p=0.027; r=0.621, p=0.001). Finally, fixation stability exhibited a non-statistical increase postoperatively.


Macular light sensitivity measurements using microperimetry seem to correlate well with type and density of cataracts. It shows sensitivity to PSC, similar to BCVA, yet also sensitivity to nuclear and cortical cataract. While the ophthalmic surgeon primarily relies on BCVA measurements to decide when to perform cataract surgery, macular light sensitivity measurements using microperimetry may further aid the surgeon on this decision. In fact, ATS measurements seem to better associate with different aspects of cataract type than BCVA. Fixation stability exhibited an unexpected tendency of decrease after surgery, yet this requires further investigation as it did not reach statistical significance.

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