Official ESCRS | European Society of Cataract & Refractive Surgeons

Changes in corneal epithelial thickness and corneal sublayer configuration after femtosecond laser small incision lenticule extraction

Session Details

Session Title: Refractive
Session Date/Time: Sunday 22/02/2015 | 08:30-11:00
Paper Time: 10:09
Venue: Sadirvan A
First Author: : N.Luft AUSTRIA
Co Author(s): :    M. Dirisamer   M. Bolz   J. Pretzl   E. Wimmer   T. Kreutzer   S. Priglinger

Abstract Details


To assess the changes in central and peripheral corneal epithelial thickness, cap thickness and residual stroma bed thickness in the first three months after ReLEx small incision lenticule extraction (SMILE).


AO – Ars Ophthalmica Study Center, Department of Ophthalmology, General Hospital Linz, Medical Faculty of Johannes Keppler University


This prospective study included patients that underwent uneventful ReLEx SMILE surgery. Anterior segment SD-OCT (RS-3000 Advance; NIDEK Co. Ltd., Aichi, Japan) was used to evaluate corneal epithelial thickness (CET), cap thickness, residual stromal bed thickness and total corneal thickness (TCT). All values were assessed at 17 points 1.25mm apart across the central 5mm of the corneal apex in the horizontal and vertical meridians. Three consecutive measurements were taken preoperatively, on the first postoperative day and 1, 6 and 12 weeks postoperatively.


Forty eyes of 20 patients were included. Mean age was 36±7.3 years. Mean spherical equivalent of the extracted lenticule was -4.92±1.25 diopters and mean lenticule thickness was 95±20µm. Preliminary results showed that mean change in central TCT from baseline was -75µm on the first postoperative day and -81µm one week postoperatively. Mean change in central CET from baseline was +1µm one day after surgery and -5µm one week after surgery. Paracentral and mid-peripheral CET change from baseline was +3µm on the first day and -2µm one week postoperatively.


Preliminary results suggest that SMILE refractive surgery induces only subtle change in CET during the first postoperative week. Furthermore, TCT seems to further decrease after the first postoperative day. A comprehensive analysis of corneal biometric changes within the central 5mm zone in the first three months after SMILE refractive surgery will be presented. Furthermore, the influence of cap thickness, refractive lenticule thickness and surgical lenticule preparation on CET and TCT over time will be analyzed.

Financial Disclosure:


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