Official ESCRS | European Society of Cataract & Refractive Surgeons

Transepithelial topography-guided PRK in corneal irregular astigmatism correction

Session Details

Session Title: Refractive
Session Date/Time: Sunday 22/02/2015 | 08:30-11:00
Paper Time: 09:57
Venue: Sadirvan A
First Author: : A.Doga RUSSIA
Co Author(s): :    E. Branchevskaya   Y. Kishkin           

Abstract Details


To assess clinical results of transepithelial topography-guided PRK for irregular corneal astigmatism correction


S. Fyodorov Eye Microsurgery Federal State Institution.


Prospective, non-comparative analysis of case series. Study group included 23 eyes of 23 patients with secondary irregular astigmatism after radial keratotomy (RK), keratitis, decentrated ablation and penetrating cornea injury. Topograpy-Guided PRK was performed using MicroScan Visum exсimer laser (Optosystems, Troitsk, Russia). Postoperative assessments - uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal topography (Tomey TMS-4, Japan), Scheimpflug-tomography (Pentacam, Oculus, Germany) ocular aberrations (OPD-Scan, Nidek, Japan) were performed at 1 week and 1, 3, 6 and 12 months post.op.


Six months after topography-guided PRK UDVA improved from 0.16±0.05 to 0.41±0.18 and CDVA from 0.54±0.11 to 0.67±0.13. Mean refraction spherical equivalent decreased from -4.38±1.05D to -1.70±0.46D. 2 eyes lost lines of CDVA: one patient with RK developed haze grade 2 and one patient had recurrence of herpes simplex keratitis 8 months after PRK. 65% of eyes gained 1 or more lines of CDVA. There was a significant improvement in ocular aberrations (point spread function and reduction of high order aberrations) and surface irregularity index


Topography-guided PRK is effective for improving visual acuity and quality of vision in patients with irregular corneal astigmatism. PRK even with small ablation depth should be considered carefully in patients with RK and herpes keratitis history.

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