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Posterior capsule opacification and Neodymium:YAG rates with 2 single-piece acrylic intraocular lenses after treatment of age-related cataracts: 3 year results

Poster Details

First Author: S.Masnec CROATIA

Co Author(s):    S. Masnec   R. Kordic   T. Kuzman   I. Skegro           

Abstract Details


The purpose of this study is to compare the incidence and intensity of posterior capsule opacification (PCO) between 2 1-piece foldable acrylic intraocular lenses (IOLs): hydrophobic acrylic intraocular lens (IOLs) and hydrophilic acrylic IOLs with different design over 3 years.


University Hospital Center Zagreb, Department of Ophthalmology, Zagreb, Croatia


83 patients with age-related cataract had phacoemulsification surgery and implantation of a Acreos Adapt AO continuous-optic-edge hydrophilic acrylic IOL and an Acrysof SA60AT interrupted-optic-edge IOL. Postoperative examinations were performed at 1 day, 1 month, 6 months and 3 years. Digital retroillumination images were taken of each eye. PCO values in the entire IOL optics area and in the central 3-mm optic zone were assessed using a photographic image analysis system (EPCO 2000) . The amount of PCO (score 0 to 10) was assessed subjectively at the slitlamp. The rate of neodymium:YAG (Nd:YAG) capsulotomy for each IOL was also compared.


The mean subjective PCO score was 2.78 ± 1.55 (SD) for the continuous-optic-edge hydrophilic acrylic IOLs and 2.32 ± 1.20 for the interrupted-optic-edge hydrophobic acrylic IOLs (P=.229). There were no significant differences in the median EPCO values in the entire IOL optics area (0.60 ± 0.26 versus 0.58 ± 0.23; P=.745) and in the central 3-mm optic zone (0.28 ± 0.13 versus 0.27 ± 0.12; P=.638) at 3 years. Three years postoperatively, a neodymium:YAG (Nd:YAG) capsulotomy was performed in 28% of eyes with the continuous-optic-edge hydrophilic acrylic IOL and 23.33% with the interrupted-optic-edge hydrophobic acrylic IOL (P=.692).


Both IOLs had comparable PCO and Nd:YAG rates 3 years postoperatively. The optimized barrier function of the continuous-optic-edge IOL and the material properties of the interrupted-optic-edge IOL seemingly outbalanced the effect on lens epithelial cell migration and proliferation beneath the optic.

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