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Association of corneal biomechanical parameters with corneal topography and refractive status in normal eyes

Poster Details

First Author: L.Papaioannou GREECE

Co Author(s):    A. Tourmouzis   K. Tourmouzis   M. Papathanassiou              

Abstract Details


To evaluate the association of corneal biomechanical properties with topographic parameters and refractive status in normal eyes.


Athens Ophthalmological Center


70 myopic and 32 hyperopic normal eyes of 51 healthy individuals were included in the study and were subdivided to different age groups (19-29 years and 30-40 years). Keratometric values were measured using Oculus Pentacam and corneal biomechanical parameters were measured using Ocular Response Analyzer. A further division of each group was performed according to the severity of myopia (spherical equivalent -1.00 D to -6.00 D and -6.00 D to -12.00 D) and the keratometric values (K2 over and under 45D). A comparison of Corneal Hysteresis (CH) and Corneal resistance factor (CRF) among the different subgroups was performed.


At the 19-29 years age group the mean CH value was 9.4 ± 1.25 SD and 13.2 ± 1.70 SD in myopic and hyperopic eyes respectively and this difference was statistically significant (P < 0.01). At the same age group the mean CRF value was 8.9 ± 0.96 SD and 12.2 ± 2.45 SD and the difference was considered statistically significant (P < 0.01), although the great difference between the SD of the two mean CRF values reduces the reliability of the comparison. No further significant difference was found among the different subgroups.


The two studied biomechanical parameters of the cornea (CH and CRF) were found more reduced in myopic than in hyperopic eyes in young adults (19-29 years), while this association does not seem to exist in older individuals. No significant association was documented in our study between biomechanical parameters and corneal topographic measurements.

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