Official ESCRS | European Society of Cataract & Refractive Surgeons
Barcelona 2015 Programme Registration Glaucoma Day 2015 Exhibition Virtual Exhibition Satellite Meetings Hotel Booking Star Alliance

Take a look inside the London 2014 Congress


Then register to join us
in Barcelona!

Living related limbal stem cell transplantation in bilateral severe ocular chemical burns

Search Abstracts by author or title
(results will display both Free Papers & Poster)

Session Details

Session Title: Cornea: Surgical II

Session Date/Time: Tuesday 08/09/2015 | 14:00-16:00

Paper Time: 15:14

Venue: Room 11

First Author: : A.El Hofi EGYPT

Co Author(s): :    A. Ghaith                    

Abstract Details


To evaluate the clinical outcome of living-related Limbal Stem Cell Transplantation in cases with bilateral severe chemical burns.


Department of Ophthalmology, Faculty of Medicine, Alexandria University, Egypt


The study involved 22 eyes with bilateral chemical burns with more than two thirds of limbal stem cell deficiency, 9-12 months after the chemical injury, no extensive conjunctival pathology, and intact lid margins. The donor was a first-degree relative, should have healthy limbal stem cells bilaterally, and screened for blood-borne diseases. Outcome measures included clarity of the cornea, regression of corneal neovascularization, regularity of corneal surface and improvement of visual acuity.


Preoperative UCVA was hand movement in 75% of eyes and counting fingers in 25% of eyes. It ranged between 1/60 and 6/60 postoperatively. Postoperative corneal status (at 6 months) 15 eyes demonstrated diminished vascularization & improved clarity. Ten eyes showed a smooth corneal surface. Four eyes suffered from a persistent epithelial defect.


Living-related LSC transplantation in bilateral severe ocular chemical burns should be attempted as it may yield some useful vision in a desperate blind patient.

Financial Interest:


Back to previous