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Filamentary keratitis epidemiology and treatment regimen

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Session Details

Session Title: Cornea - Medical

Session Date/Time: Monday 07/09/2015 | 08:00-10:30

Paper Time: 09:06

Venue: Room 17

First Author: : I.Pronkin RUSSIA

Co Author(s): :    D. Maychuk                    

Abstract Details


To analyze concomitant pathology contributing to filamentary keratitis and to evaluate effectiveness of different treatment regimens.


Fyodorov Eye Microsurgery Complex, Moscow, Russia


We examined 38 patients (76 eyes) with filamentary keratitis. All of them were consulted by co-specialists (internist, endocrinologist, reumatologist) with the object to reveal concomitant diseases. All patients were divided into 3 groups depending on treatment regimen. The treatment included keratoprotectors, artificial tears, reparative eyedrops and one of the following components: Vitabact (1st group), Dexamethasone (2nd group), Restasis (3rd group). Besides, in case of decompensated concomitant disease, patients were treated by appropriate specialist. Among investigative methods were: patients' questionnaire, biomicroscopy, 5-region corneal fluorescein staining scale, Shirmer test – 1, TBUT- test. Follow-up period was 6 months.


Among concomitant pathology we revealed: Thyroid gland disfunction (34,2 %), rheumatoid arthritis (21,1 %) and their combination (10,5 %), Sjögren's Syndrome (2,6 %); II type diabetes mellitus (7,9 %); Combination of diabetes and thyroid gland dysfunction (13,2 %) and neither endocrine nor rheumatoid diseases (10,5 %). Shirmer test – 1 results were variable and no appropriateness with treatment regimen was found. TBUT-test data before treatment were low (6-9 sec.) with an increase up to 9-11 sec. after the treatment.


Dexamethasone as a component of combined therapy contributed to rapid filaments' resorbtion, Restasis – to fast effect and stable remission. 89.5 % of patients had endocrine pathology or rheumatoid diseases or their combination. With this in view, we may consider filamentary keratitis not as a form of severe dry eye syndrome, but as a separate dystrophic corneal disorder with dry eye as its symptom.

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