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Topograph-guided photorefractive keratectomy in patient with post-infectious anterior stromal opacity and induced irregular astigmatism: clinical case report

Poster Details

First Author: R.Makarov RUSSIA

Co Author(s):    I. Mushkova   Y. Kishkin   N. Maychuk        

Abstract Details


The aim of this study was to assess the possibility of application and clinical results of topography-guided photorefractive keratectomy (topo-PRK) in patient with post-infectious anterior stromal opacity and induced irregular astigmatism


Sv. Fyodorov Eye Microsurgery Federal State Institution


We report the clinical findings of a case of anterior paracentral stromal corneal opacity due to herpetic stromal keratitis. An 21-year-old women presented with low uncorrected visual acuity (UCVA) and corrected visual acuity (BCVA) of right eye. This patient underwent the topo-PRK using MicroScan eximer laser 500 Hz (Optosystems, Russia). The ablation profile was calculated using the KeraScan software (Optosystems, Russia). Examination included: UCVA, BCVA, corneal topography indexes (Surface irregularity index (SRI), surface asymmetry index (SAI)), evaluation of refraction before and 1 year post-op. Preoperative and postoperative corneal thickness a Fourier domain optical coherence tomography was also examined


UCVA 1 year post-op was 20/28 compared to 20/285 preoperatively; BCVA was 20/20 compared to 20/50 preoperatively. The spherical component of the refraction was -0.25 D compared to -8.0 D preoperatively. The cylindrical component was -3.5 D compared to -9.0 D preoperatively. SRI pre-op.: 1.85, post-op.: 0.47; SAI pre-op.: 2.09, post-op.: 1.24. Central corneal thickness after surgery was 407μm in comparison with 547μm before surgery and minimal corneal thickness was 359 μm compared to 368 μm pre-op). No herpetic keratitis recurrence was detected up to 1 year after surgery.


This clinical case shows that topography-guided photorefractive keratectomy with Russian made excimer laser and software is a possible method for visual rehabilitation in patients with anterior stromal corneal opacity and allows achieving a high clinical and functional result FINANCIAL DISCLOUSRE: NONE

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