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Effects of femtosecond and excimer lasers on implanted KAMRA corneal inlay: an experimental study

Poster Details

First Author: F.Sammouh LEBANON

Co Author(s):    W. Dandan   E. Warrak           

Abstract Details


To evaluate effect of femtosecond laser and excimer laser on implanted KAMRA corneal inlay.


Advanced Eye Care Hospital


Femtosecond laser was used to create an intrastromal pocket at 250um depth in a pig’s eye cornea. KAMRA corneal inlay (KAMRA#1) was implanted in the pocket followed by a standard LASIK flap creation using femtosecond laser at 110um. KAMRA#1 was explanted and examined by slit-lamp biomicroscopy (SLB). A new KAMRA inlay (KAMRA#2) was implanted in the same pocket followed by standard (under the flap) excimer laser ablation (-3.00 targeted refraction. KAMRA#2 was explanted and examined by SLB. The same inlay was then reimplanted in the same pocket followed by a second similar excimer laser ablation then explanted and examined.


The two KAMRA (#1 and #2) inlays were examined by SLB under high magnification before and after application of femtosecond (KAMRA#1) and excimer (KAMRA#2) laser after being implanted in an intrastromal pocket. A significant burn and shrinkage was noted on KAMRA#1 following superficial femtosecond laser flap creation. However, no apparent effect was noted on KAMRA#2 following repeated excimer laser ablation.


KAMRA inlay appears to absorb femtosecond laser energy leading to significant damage in the inlay. No significant effect of excimer laser was noted on implanted KAMRA inlay. Therefore, unlike excimer laser, femtosecond laser seems to be hazardous and harmful to the KAMRA inlay when used after implantation. When refractive enhancement is needed after KAMRA inlay implantation, femtosecond laser should not be used for flap creation. Supplementary studies are needed to further evaluate the effect of excimer laser on implanted KAMRA inlay and surrounding corneal stroma. FINANCIAL DISCLOUSRE: NONE

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