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Retidyne™ CAP: efficacy and safety of a lutein-based dye in staining the anterior capsule during phacoemulsification

Poster Details

First Author: J.Duarte PORTUGAL

Co Author(s):    M. Monteiro   A. Lima   D. Sousa-Martins   M. Maia   R. Belfort Jr  

Abstract Details


The main purpose of this study was to evaluate the safety and efficacy of using Retidyne™ CAP for staining the anterior capsule preceding capsulorhexis, a critical step during cataract surgery. Three formulations of Retidyne™ CAP containing different concentrations of lutein and brilliant blue were evaluated, analyzing their impact on the surgery procedure and outcomes.


The CIP was approved by the IRB at UNIFESP-School of Medicine (Universidade Federal de São Paulo, Escola Paulista de Medicina).


Phacoemulsification was performed in 9 patients with diagnosed cataracts in both eyes. Patients were divided in three groups and capsulorhexis was done using Retidyne™ CAP formulation 1, 2 or 3. A questionnaire evaluating surgeons’ opinion on the dye efficacy and safety was filled at the end of each surgery. Follow up examinations were performed at days 1, 7 and 30 post-surgery.


All patients recovered their BCVA values after surgery (30d), reaching a mean value of 20/20 in all patients. No signs of toxicity or side effects were observed, and IOP post-surgery was maintained or reduced. Retidyne™ CAP was considered adequate and useful for anterior capsule identification, improving its visualization, and being totally removed in the end of the surgery.


Results suggest that all Retidyne™ CAP formulations improved anterior capsule visualization, allowing a good staining, with no reported side effects. Therefore, this lutein-based dye was proven adequate and safe for the anterior capsule staining in cataract surgery. This is in agreement with previous lutein-based dyes studies in which safety is well documented. FINANCIAL DISCLOUSRE: One or more of the authors is employed by a for-profit company with an interest in the subject of the presentation

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