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Nanosecond laser cataract surgery: contralateral endothelial cell study

Poster Details

First Author: G.Chatzilaou GREECE

Co Author(s):    A. Kanellopoulos   G. Asimellis           

Abstract Details


The purpose of this study was to contralaterally evaluate and compare corneal endothelium cell density and morphology after coaxial ultrasound phacoemulsification and novel coaxial nanosecond laser-assisted phacoemulsification for cataract surgery

Setting: Clinical and Research Eye Institute, Athens, Greece


Eighty-two eyes (41 patients). Each patient received ultrasound coaxial phacoemulsification (US) on one eye and coaxial nanosecond-laser-assisted cataract surgery (NL) on the other. Nuclear sclerosis graded from NO3NC3 to NO4NC4 using Lens Opacities Classification System. Parameters analyzed: effective phacoemulsification time (EPT) for ultrasound group-A and number of laser pulses and total energy used for the nanosecond laser group-B. Endothelial cell density (ECD) and endothelial cell size variability were determined preoperatively and two years postoperatively. Endothelial structure was evaluated by endothelial cell density (cells/mm2), coefficient of variation (CV) in cell size (polymegethism), and percentage of hexagonal cells (%HC) – pleomorphism.


Mean EPT in ultrasound group-A was 7.26±44seconds. In nanosecond-laser group-B average number of laser pulses was 243±188. Each pulse released 7.5 mJ of 14ns duration. Dissipated energy 1.83 J. Mean preoperative ECD in group-A was 2517±137 cells/mm2 and two-years postoperatively 2287±155 cells/mm2 (p<0.001). In nanosecond-laser group-B 2521±233 cells/mm2 and 2420±292 cells/mm2 (p<0.001). Mean preoperative CV in group-A was 27.6±2.4 and two-years 30.6±2.4 (p<0.001). In nanosecond laser group-B, 27.9±2.8 and 27.2±2.0 (p<0.001). Mean %HC in ultrasound group-A was preoperatively 42.3±3.6 and two-years postoperatively 37.74±3.54 (p<0.001). In nanosecond laser group-B, 42.8±3.2 and 43.00±2.68 (p<0.001).


Data in this study indicate that nanosecond laser-assisted cataract surgery phacoemulsification presents some advantages in comparison to ultrasound phacoemulsification in relation to endothelial cell structure preservation. FINANCIAL DISCLOUSRE: One or more of the authors travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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