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Visual outcomes, quality of vision, and patient-reported outcomes: trifocal intraocular lens vs. extended depth of focus intraocular lens

Poster Details

First Author: D.Tran USA

Co Author(s):    R. Potvin   A. Owyang   J. Hwang              

Abstract Details


To evaluate patients’ visual acuity, spectacle independence, quality of vision, and contrast sensitivity, comparing results from bilateral implantation of AcrySof® IQ PanOptix® trifocal intraocular lens and bilateral implantation of Tecnis Symfony® extended depth of focus intraocular lens.


One clinical practice in Orange, CA, USA.


This was a prospective, non-interventional, masked, two-arm comparative study of outcomes following successful, uncomplicated bilateral cataract surgery. Subjects were assessed during a single visit, 3 to 24 months after surgery. Visual acuity measures included the uncorrected and best distance-corrected binocular near, intermediate, and distance visual acuity (measured at 40cm, 60cm, and 4-6m respectively), with the distance-corrected near visual acuity of most interest. Other measures included a spectacle independence questionnaire, a quality of vision questionnaire and best-corrected binocular distance contrast sensitivity (mesopic and photopic). Nineteen EDOF and 13 trifocal subjects have been evaluated to date, matched for age and sex.


The spherical equivalent refraction (p = 0.28) and refractive cylinder (p = 0.92) were not significantly different between groups. The EDOF group had a mean distance corrected VA (DCVA) better than the trifocal group (p < 0.01) but both were better than 20/20. The trifocal distance corrected intermediate VA was one line better and near VA was 2 lines better than the EDOF group (p < 0.01 for both). The reported need for spectacles at near was higher in the EDOF group (p = 0.02). Contrast sensitivity was similar between IOLs in photopic (p = 0.11) and mesopic (p = 0.05) conditions.


Similar refractive results were observed between the IOL groups. They had similar contrast sensitivity, suggesting comparable visual quality. The major difference was the better distance VA with the EDOF lens and the better near and intermediate VA with the trifocal lens, with the trifocal group reporting a much lower need for spectacles at near.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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