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Aberrometric changes after corneal collagen cross-linking in patients with corneal ectasia

Poster Details

First Author: P.Dominguez Castillo MEXICO

Co Author(s):    M. Benedetti Sander   C. Hernández   V. Sánchez Huerta              

Abstract Details


To assess high-order aberrations (HOAs) induced after crosslinking in patients with keratoconus.


Cornea and External consultation. Asociación para Evitar la Ceguera en México I.A.P.


Prospective, longitudinal, interverntionist and descriptive study. Patients who had previous diagnosis of keratoconus with topography (Pentacam), measurement of aberrometries was performed (OPD3) precrosslinking and 90 days after. Inclusion criteria: Patients with maximum keratometry less than 60 diopter, spherical equivalent less than 10, signed informed consent. Exclusion criteria: Younger than 18 years old, pregnancy o lactation, , preexisting corneal diseases, systemic diseases, post refractive surgery ectasia.


81 eyes (55 patients) with keratoconus subjected to crosslinking. 42 (51.9%) were male. Average age: 25.5 ± 12.3 (11-78 años). Coma (90°): precrosslinking was -0.95 ± 1.26 and postcrosslinking was -0.73 ± 1.1 (p=0.003). Coma (0°): precrosslinking was -0.21 ± 1.05 and postcrosslinking was 0.16 ± 0.92 (p=0.78). RMS (Root Media Square): recrosslinking was 1.56 ± 1.09 and postcrosslinking was 1.37 ± 0.84 (p=0.0002).


By comparing the measurements pre and postcrosslinking, we found a statistically significant reduction of the 90° coma and RMS postcrosslinking, while the 0° coma did not hace modifications

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