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Outcomes of descemet membrane endothelial keratoplasty in eyes with glaucoma, maculopathy and previous corneal transplants

Poster Details

First Author: E.Nche ISRAEL

Co Author(s):    T. Batash   A. Katsir   A. Solomon   L. Itay           

Abstract Details


To evaluate the outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) in patients with ocular morbidities in comparison to patients without.


Hadassah-Hebrew Univeristy Teaching Hospital, Jerusalem , Israel.


Sixty-five DMEK procedures performed in sixty-three eyes of sixty-two patients with corneal edema were retrospectively reviewed. The main outcomes were corrected distance visual acuity and the frequency of graft failure at six months follow up. Eyes were separated into six groups as follows and analyzed: Glaucoma Only (GO), Glaucoma and Maculopathy (GM), Glaucoma and previous Corneal transplant (GC), previous Corneal Transplant (CT), Maculopathy Only (MO) and No associated glaucoma, maculopathy or corneal transplant (N).


Corrected median distance visual acuity (logMar) improved in all groups from before surgery to six months follow up. In order of best outcome: N group; 0.8 [0.4, 2] to 0.3 [0.1, 1], CT group; 2 [0.2, 3] to 0.4 [0.18, 1.3], GM group; 1.5 [0.3,3] to 0.5 [0.4,1], MO group; 0.5 [0.2, 2] to 0.5 [0.1, 2], GO group; 2.0 [0.4, 3] to 0.7 [0.1, 2], GC group; 1.5 [0.7,2] to 1.35 [0.2, 2]. Thirteen eyes (20%) had graft failure by the sixth month of follow up, four in the GC group (44.4%), and three in the CT group (25%).


DMEK leads to improved vision in eyes with associated glaucoma, maculopathy or previous corneal transplants. However, eyes with glaucoma experience the least improvement in visual acuity especially in eyes that have undergone a previous corneal transplant. In these eyes, graft failure rates are the highest.

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