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The value of OCT-SA in monitoring amniotic membrane transplantation

Poster Details

First Author: M.Mouajab MOROCCO

Co Author(s):    C. Khodriss   A. Bennis   F. Chraibi   M. Abdellaoui   I. Benatiya Andaloussi        

Abstract Details


Corneal perforation is a frequent situation in an ophthalmological emergency. The amniotic membrane retains its place in their management, by promoting corneal epithelialization using its anti-fibrotic, anti-inflammatory, anti-angiogenic and antimicrobial characteristics. The aim of our work is to analyze the structural characteristics of the cornea and the amniotic membrane after its integration into the cornea using OCT-SA.


Ophthalmology department, Hassan II University Hospital Center (University of Sidi Mohammed Ben Abdellah).FEZ. Morocco.


This is a prospective study covering 37 cases of corneal perforations, deep ulcers or pre-perforation. The post-operative monitoring parameters were: an examination at the LAF and an OCT-SA, on D2, D7,D14 and D28.


Our study reports 37 eyes. Mean age was 48.6 years with a male predominance in 67% of cases. The OCT-SA was performed before the surgical procedure. At D2; the average thickness of the amniotic membrane was 210 µm. At D7; this thickness has decreased to 112 µm. On D28, more than 96% of the patients integrated the membrane into the corneal thickness, with an average corneal thickness of 495 µm.The best visual acuity with correction was greater than 5/10 in 2 patients, after an average follow-up of 6 months.


The amniotic membrane transplant is the best alternative in the management of corneal perforations and pre-perforative ulcers. Its integration into the corneal thickness is always associated with its re-epithelialization. The OCT-SA is the best way for better monitoring of the integration of this membrane.

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