The value of OCT-SA in monitoring amniotic membrane transplantation
First Author: M.Mouajab MOROCCO
Co Author(s): C. Khodriss A. Bennis F. Chraibi M. Abdellaoui I. Benatiya Andaloussi
Corneal perforation is a frequent situation in an ophthalmological emergency. The amniotic membrane retains its place in their management, by promoting corneal epithelialization using its anti-fibrotic, anti-inflammatory, anti-angiogenic and antimicrobial characteristics. The aim of our work is to analyze the structural characteristics of the cornea and the amniotic membrane after its integration into the cornea using OCT-SA.
Ophthalmology department, Hassan II University Hospital Center (University of Sidi Mohammed Ben Abdellah).FEZ. Morocco.
This is a prospective study covering 37 cases of corneal perforations, deep ulcers or pre-perforation. The post-operative monitoring parameters were: an examination at the LAF and an OCT-SA, on D2, D7,D14 and D28.
Our study reports 37 eyes. Mean age was 48.6 years with a male predominance in 67% of cases. The OCT-SA was performed before the surgical procedure. At D2; the average thickness of the amniotic membrane was 210 µm. At D7; this thickness has decreased to 112 µm. On D28, more than 96% of the patients integrated the membrane into the corneal thickness, with an average corneal thickness of 495 µm.The best visual acuity with correction was greater than 5/10 in 2 patients, after an average follow-up of 6 months.
The amniotic membrane transplant is the best alternative in the management of corneal perforations and pre-perforative ulcers. Its integration into the corneal thickness is always associated with its re-epithelialization. The OCT-SA is the best way for better monitoring of the integration of this membrane.