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Intrastromal keratophakia treatment in advanced keratoconus cases

Poster Details

First Author: J.Moore UK

Co Author(s):    R. McNeely                    

Abstract Details


To outline the efficacy of implanting a Xenia lenticule in cases of ectasia due to advanced keratoconus.


Cathedral Eye Clinic, Belfast, Northern Ireland, UK


Four eyes of 4 patients (2 female and 2 male) with ectasia due to advanced keratoconus were included. In these cases, the Xenia lenticule (Gebauer Medical) was utilized which is a highly cross linked corneal button of porcine tissue, with a diameter of 7mm. In each case a 7.25 mm diameter pocket was created using the Visumax Zeiss Meditec machine and a 180 micron cap was used. Corrected distance visual acuity (CDVA), mean keratometry readings, and central corneal thickness (CCT) were outlined 6 months postoperatively.


Average preoperative Ks were 62.06 ± 8.40 D reducing to 57.48 ± 5.71 D 6 months postoperatively. Preoperative central corneal thickness was 352 ± 40.08 um with Scheimpflug imaging (Pentacam) compared to 523.8 ± 18.45um postoperatively measured with anterior segment OCT. Six-month postoperative CDVA was 1.25 ± 0.35 logMAR. Visual acuity with a hard contact lens was measured in each case with a mean CDVA of 0.45 ± 0.17 logMAR (range: 0.2, 0.7 logMAR). Each case will receive topoguided TransPRK treatment and the results will be presented at the conference.


Intrastromal keratophakia provides an effective methodology to stabilize the cornea and avoid the need for whole corneal transplantation in advanced keratoconus cases.

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