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Global prevalence, patient and economic burden of presbyopia: a systematic literature review

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First Author: C.Balachandran AUSTRALIA

Co Author(s):    J. Berdahl   M. Dhariwal   J. Lemp-Hull   D. Thakker           

Abstract Details


Presbyopia is an impairment of near vision characterized by gradual loss of the ability of the eyes to focus on nearby objects. It is a common or nearly universal condition in older-aged adults (>65 years) and poses a burden on patients and healthcare systems. The objective of the present study was to collate and report published evidence on Presbyopia burden (prevalence, impact on patient quality of life and associated costs).


Systematic Literature Review of published evidence.


A systematic search was conducted in the MEDLINE®, Embase®, and Cochrane Library databases from the time of inception through October 2018. Studies published in the English language reporting the epidemiology and patient and economic burden of presbyopia were included. Overall, 64 studies were included for data extraction and reporting.


Global presbyopia prevalence is predicted to increase from 1.1 billion in 2015 to 1.8 billion by 2050. In 2010, 43.8% of adults ≥40 years in Japan suffered from presbyopia. In rural China, functional presbyopia affected 67.3% of adults ≥40 years. Uncorrected presbyopia increases odds of difficulty in performing near-vision tasks and very demanding near-vision tasks by 2-fold and >8-fold, respectively. Uncorrected Presbyopia combined with uncorrected distance vision impairment significantly affects patients’ quality of life. Globally, potential productivity loss due to uncorrected or under-corrected presbyopia in individuals aged <50 years is estimated at US $11 billion [0.02% of global GDP].


Presbyopia poses significant burden to societies, and requires timely and optimal correction to minimize impact on vision quality and productivity.

Financial Disclosure:

... is employed by a for-profit company with an interest in the subject of the presentation

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