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To evaluate endothelial cell count loss after five years following phakic intraocular lens insertion

Session Details

Session Title: Phakic IOLs and keratoconus or high astigmatism

Session Date/Time: Sunday 06/10/2013 | 17:00-18:30

Paper Time: 17:00

Venue: Elicium 1 (First Floor)

First Author: : C.Baily IRELAND

Co Author(s): :    M. O"Keefe              

Abstract Details


To determine if Artisan or Artiflex phakic intraocular lens (pIOL) implantation cause significant endothelial cell loss after five years in myopic and hyperopic eyes.


Department of Refractive Surgery, Mater Private Hospital, Dublin, Ireland.


Prospective, non-randomised clinical study. The study included 200 eyes of 120 patients aged between 21 and 60 years. Inclusion criteria included absence of ocular pathology, refraction outside the parameters for conventional laser refractive surgery, endothelial cell count (ECC) of > 2000 pre-operatively and anterior chamber depth of >3.2mm, ECC was determined pre-operatively and then yearly post-operatively. On-going analysis includes the calculation of pIOL-endothelium depth and lens-pIOL depth (using Optical Coherence Tomography), and to determine if these results are correlated with any changes in ECC.


Preliminary results demonstrated a mean pre-operative ECC of 3034.51±511.44 cells/mm2, a mean one year ECC of 3085.04±421.85 cells/mm2 (p=0.55) and a mean five year ECC of 2714.20±284.74 cells/mm2 (p=0.00). This was a mean gain in ECC from baseline of 1.7% at one year and a mean loss of 10.0% at five years


We demonstrated no significant loss in ECC after 1 year, with a 10% loss at five years following pIOL insertion.

Financial Interest:


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