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Evaluation of clarity characteristics in a new hydrophobic acrylic IOL in comparison with commercially available lenses

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Session Details

Session Title: Cataract Surgery Complications: IOL Dislocation and Opacification

Session Date/Time: Tuesday 10/10/2017 | 14:00-16:00

Paper Time: 15:48

Venue: Room 3.6

First Author: : L.Werner USA

Co Author(s): :    I. Thatthamla   M. Ong   K. Das   H. Schatz           

Abstract Details


To perform an in vitro assessment of surface haze, subsurface nanoglistenings (SSNG), as well as glistenings formation of a new hydrophobic acrylic intraocular lens (IOL), and compare it with commercially available hydrophobic acrylic lenses.


John A Moran Eye Center, University of Utah, Salt Lake City, Utah, USA, Alcon Laboratories, Inc., Fort Worth, Texas, USA.


IOL models used were Alcon Clareon SY60WF, AMO Tecnis ZCB00 and Tecnis OptiBlue ZCB00V, Santen Eternity W-60, B&L enVista MX60, and Hoya Vivinex XY1. Haze was assessed by the pixel intensity (PI) of anterior/posterior surfaces of the IOLs from cross-sectional slit lamp images (BX-900 Haag-Streit). For SSNG assessment, IOLs were subjected to accelerated aging up to 10 yrs. (81 days in BSS at 90°C) followed by Scheimpflug densitometry measurements (EAS-1000 Nidek). For glistening assessment, IOLs were loaded into a 45 °C water bath for 24 hours, then moved into a 37 °C water bath for 2.5 hours prior to analysis.


Surface haze (N=10, values in PI) was: 4.25 ± 0.87 (SY60WF), 9.50 ± 1.66 (ZCB00), 39.48 ± 1.97 (ZCB00V), 46.68 ± 3.16 (W-60), 44.70 ± 4.00 (MX60), and 4.42 ± 0.71 (XY1), P<0.001 (One Way ANOVA). Densitometry (N=10) after aging was (values in CCT): 7.30 ± 1.36 (SY60WF), 11.88 ± 3.10 (ZCB00), 38.12 ± 2.24 (ZCB00V), 48.13 ± 9.44 (W-60), 20.20 ± 3.84 (MX60), and 6.75 ± 6.66 (XY1), P<0.001 (One Way ANOVA); no difference between SY60WF vs. ZCB00 and XY1. Microvacuole density (N=30) was the lowest for SY60WF and MX60 lenses (0.62 +/- 0.94, and 0.06 +/- 0.31 mV/mm2).


Nano and micro-sized surface and bulk inhomogeneities of IOLs may be associated with increased light scattering. The new IOL model SY60WF is manufactured from a hydrophobic acrylic material exhibiting very low levels of surface haze, SSNG, and glistening formation.

Financial Disclosure:

is employed by a forNONEprofit company with an interest in the subject of the presentation

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