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Peripapillary retinal nerve fiber layer thickness vs macular thickness in early diagnosis of primary open-angle glaucoma using optical coherence tomography angiography

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Session Details

Session Title: Glaucoma

Session Date/Time: Monday 09/10/2017 | 08:00-10:30

Paper Time: 08:00

Venue: Room 4.1

First Author: : A.Usman BELARUS

Co Author(s): :    L. Marchenko   T. Kachan                 

Abstract Details


To identify informative accuracy of thickness of the peripapillary retinal nerve fiber (RNFL) and the macular in early detection of glaucomatous optic neuropathy (GON) using the optical coherence tomography Angiography (OCTA) ‘optoveu’


3rd Minsk City Hospital named after E.V. Klumove,Department of Ophthalmology, Belarusian State Medical University, Republic of Belarus


Included in our study were 46 eyes of 23 patients with stage I primary open angle glaucoma (POAG) as the main group, 34 eyes of 17 glaucoma suspects and 20 eyes of 10 healthy subjects as the control group. All subjects underwent OCTA scanning of the retina using RTVue100 “Оptovue” model. The ‘ONH scan’ and ‘Retina Thickness Map program’ were respectively used to scan the 3.45 mm perepapillary and a 5mm x 5mm region of the macular regions.


Patients in the stage I POAG group had significant decrease in all parameters of the paripapillary RNFL and perifoveal macular thickness compared to the control group. Inter-group analysis using Mann-Whitney criteria revealed statistically significant differences between the main and control groups in superior and inferior RNFL thickness only. In the macular region, statistically significant differences between patients with stage I POAG and healthy individuals were identified in total average, temporal and nasal perifoveal macular thickness. Similar result were noticed between the stage I POAG and glaucoma suspects groups. There were no differences between the glaucoma suspect and the control groups.


In early detection of glaucomatous optic neuropathy, macular thickness is more informative as compared to the peripapillary RNFL thickness using the OCTA optovue

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