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Short-term safety and efficacy of combined laser-assisted subepithelial keratomileusis and accelerated corneal cross-linking for myopia

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Session Details

Session Title: Advanced Surface Photoablation I

Session Date/Time: Sunday 08/10/2017 | 08:00-09:30

Paper Time: 09:15

Venue: Meeting Center Room I

First Author: : J.Chung SOUTH KOREA

Co Author(s): :    K. Kim   K. Koh   Y. Kwon   S. Song   B. Kim        

Abstract Details


To evaluate a short-term safety and efficacy of LASEK-Xtra, a technique combining laser-assisted subepithelial keratomileusis (LASEK) and accelerated corneal crosslinking (CXL) for myopia compared with the outcomes of standard LASEK.


Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Korea.


136 myopic eyes undergoing LASEK-Xtra from July, 2015 to January, 2016 and control group of 102 myopic eyes undergoing LASEK from January, 2015 to December, 2015 were retrospectively analyzed. Manifest refractive spherical equivalent (MRSE), corneal keratometry (K), uncorrected (UDVA) and corrected (CDVA) distance visual acuities and complications were analyzed both preoperatively and postoperatively for 6 months.


The mean preoperative MRSE was significantly -6.23±0.18 diopter (range,-10.75~-1.00D) in the LASEK-Xtra eyes, -4.55±0.17 diopter (range,-8.50~-1.50D) in the LASEK eyes. The differences between the 2 groups were statistically significant (p<0.05). Postoperative UDVA and MRSE at 6 month was not significantly different statistically between the 2 groups (LASEK-Xtra: 0.06±0.003 logMAR, -0.005±0.03 D, LASEK: 0.01±0.003 logMAR, -0.02±0.03 D). Linear regression of the scatterplot of attempted versus achieved correction reveals a coefficient of determination of R2=0.977(p<0.05) in the LASEK-Xtra group vs R2=0.978(p<0.05) in the LASEK group.


Combined LASEK and accelerated corneal crosslinking does not reduce the accuracy of the postoperative visual acuity and refraction in myopic subjects with higher diopters compared to LASEK surgery. In terms of the predictability of refractive outcomes, LASEK-Xtra is considered as an effective and safe surgical procedure in comparison with LASEK surgery.

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