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Risk factors in glaucoma patients

Poster Details

First Author: M.Karageorgieva BULGARIA

Co Author(s):    R. Hristova              

Abstract Details


To study the frequency of risk factors for progression among glaucoma patients treated in the clinic


: Queen Joanna University Hospital - Ophthalmology Department - Sofia, Bulgaria


The research is retrospective and includes 466 patients with glaucoma and ocular hypertension treated in the clinic from 01.01.2010 to 01.07.2011. All patients have been obligatory fully examined as follows: visual acuity with correction, biomicroscopy, gonioscopy of iridocorneal angle, IOP fluctuation, fundoscopy, perimetry, CCT. The main risk factors that may influence the progression of glaucoma have been examined.


Risk Factors are examined among 466 patients with glaucoma (100%) 1. Age - 412 patients (88.4%). 2. High IOP - 446 patients (100%). 3. Myopia - 75 patients (16%). 4. Family history - 20 patients (4.3%). 5. CCT (measured in 100 patients) - 65 patients (65%). 6. Arterial hypertension - 230 patients (49.4%). 7. Vascular pathology - 101 patients (21.7%). 8. PEX - 92 patients (19.7%.) 9. Diabetes ? - 35 patients (7.5%). 10. Others* 92 patients (19.7%). *Over 30 other diseases are risk factors and are grouped as “others”: Endocrine (without diabetes) – most commonly Hashimoto thyroiditis; Autoimmune – RA; Bone/tendon degenerations – arthroses. Distribution by gender: Women: 330 patients (70.8%); Men: 136 patients (29.2%). Distribution by age: 0-18 years: 1 patient (0.2); 19-45years: 46 patients (9.9%); 46-65 years: 54patients (11.6%); Over 66 years: 365 patients (78.3 %).


According to the results of our study the frequency of glaucoma is higher in women and in the age over 45. There is a big variety of risk factors as trigger mechanism for glaucoma as is the risk of progression. The most common risk factors are: high IOP, age, CCT, arterial hypertension, PEX, vascular pathology, etc. A fact of interest is the frequency of autoimmune diseases, associated with glaucoma, which supports the presence of similar mechanisms for development of these two pathologies. There is a hypothetic connection between glaucoma and Hashimoto’s disease. Some bone tendon degenerative diseases also show association with the development of glaucoma.

Financial Disclosure:


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