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Visual outcomes of refractive lenticule extraction compared to femtosecond LASIK for myopia and myopic astigmatism

Poster Details

First Author: M.Ang SINGAPORE

Co Author(s):    J. Mehta   D. Tan           

Abstract Details


To compare the efficacy, safety and predictability of Refractive Lenticule Extraction (ReLEx) with femtosecond Laser in-situ keratomileusis (LASIK) for myopia and myopic astigmatism.


Prospective multi-surgeon study performed at a single tertiary center


We studied 85 eyes that underwent ReLEx (40 eyes Femtosecond Lenticule Extraction (FLEx) and 45 eyes pseudo-Small Incision Lenticule Extraction (pSMILE)) between Mar 2010 and Mar 2011 using the VisuMax 500kHz femtosecond laser system (Carl Zeiss Meditec, Germany). Preoperative, 3-month postoperative manifest refractions, attempted treatment spherical equivalents (SE), uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) were documented. Data was compared to age- and refraction-matched results of LASIK performed using the VisuMax 500kHz femtosecond and WAVELIGHT Allegretto 400Hz(Alcon, USA) excimer systems during the same period.


Preoperative mean SE was -5.84+/-1.91D and -6.13+/-1.49D, with 3-month postoperative SE of 0.07+/-0.53D and 0.06+/-0.39D for ReLEx and LASIK respectively. Overall efficacy index for ReLEx was 0.90, 98.2% achieving UCVA of 20/40 or better, and 63% 20/20 or better. LASIK achieved 0.93 (p=0.23), with 99.6% UCVA 20/40 or better, and 78.3% 20/20 or better. 96.3% achieved +/-1.0D of target for ReLEx compared to 97.8% for LASIK (p=0.38). Overall safety indices were 1.04 and 1.05 (p=0.55).


ReLEx with the VisuMax system demonstrates safety, efficacy and predictability profiles comparable to those of LASIK performed with the VisuMax and Allegretto systems. FINANCIAL DISCLOSURE?: No

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