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Comparison of the Endosaver with non-injector techniques in descemet stripping endothelial keratoplasty

Poster Details

First Author: M.Tsatsos UK

Co Author(s):    R. Krishnan   C. MacGregor   P. Hossain   D. Anderson     

Abstract Details


To describe and evaluate the use of an injector device the Endosaver for inserting the graft in manually dissected descemet-stripping endothelial keratoplasty (DSEK) and compare it with Non injector insertion techniques.


Southampton University Hospital NHS Trust


Interventional case series. Assessment of outcomes of DSEK using the Endosaver injector compared to non-injector (forceps or glide). Postoperative specular microscopy and manifest refraction at 12 months post-operatively were evaluated


No significant statistical difference was found in pre-operative and post-operative best corrected visual acuity between the Endosaver and non-Endosaver insertion groups. Mean pre-operative endothelial cell count was 2667 (±130) for the Endosaver group and 2621 (±102) for the non-Endosaver group. Post-operative endothelial counts showed a significant difference between the Endosaver 1593 (±567) and the non-Endosaver 1017 (±468) insertion groups.


The Endosaver device allowed less trauma during graft insertion due to the minimal touch technique employed. A smaller insertion wound of 4.5 mm compared to non-injector cases enabled a more stable system during surgery. Mean postoperative donor endothelial cell counts were higher in the Endosaver group (P= 0.015) suggestive of less endothelial damage during insertion. FINANCIAL DISCLOSURE?: No

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