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Posterior capsular opacification and YAG capsulotomy rates: hydrophobic and hydrophilic lens compared

Poster Details

First Author: S.Maqsood UK

Co Author(s):    G. Smith              

Abstract Details


Posterior capsular opacification (PCO) is one of the frequent long -term complications following cataract surgery. There are multiple factors thought to be involved in development of PCO including intra-ocular lens (IOL) material, IOL design, and surgical technique. We present a comparison of PCO progression and Yttrium Aluminium Garnet (YAG) capsulotomy rates between a hydrophobic and hydrophilic lens material with a common edge design and surgical technique.


Great Western Hospital, a District General Hospital of south –west of England.


A total of 200 uncomplicated consecutive cataracts operated by one surgeon and transplanted with the MI60 and the SA60 lens (100 each) were retrospectively assessed for degree of PCO with a follow up period of 24 months. Furthermore, YAG capsulotomy rates are calculated and compared.


At one year, 12 of the patients with MI60 lens had developed mild PCO (compared to 8 patients with SA60 lens, Fisher exact test p value: 0.26). Three patients with MI60 lens were assessed to have moderate PCO (compared to 1 patient with SA60, p value: 0.31), No MI60 patients had developed severe PCO (compared to 2 patients with SA60). Three percent of patients with MI60 lens had undergone YAG capsulotomy at 1 year, as opposed to two percent capsulotomy rate with SA60 lens (p value: 0.50). At two years, patients with the MI60 lens developing mild and moderate PCO were 14 and 3, compared to 14 and 5 with the SA60 respectively (p value: 0.26, 0.50). YAG capsultomies were performed for six patients with MI60 compared to four patients with SA60 lens (p value: 0.34) at the end of 24 month follow up


When compared with SA60 lens, MI60 lens has shown increased progression of PCO and YAG Capsulotomy rates but the difference is not significantly different at 2 years. Despite these findings, the MI60 lens offers the advantages of smaller incision size, low aspheric aberrations and glistening. FINANCIAL DISCLOSURE?: No

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