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Pseudophakic intraocular lens explantation: morphological differences observed by scanning electron microscopy according to the reason for IOL explantation

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Session Details

Session Title: Presented Poster Session 08: Cataract Surgery Complications / Management

Session Date/Time: Sunday 14/09/2014 | 09:30-11:00

Paper Time: 09:45

Venue: Pod 2 (Poster Village)

First Author: : R.Fernández-Buenaga SPAIN

Co Author(s): :    J. Alio   J. Ramirez   J. Prause   A. Ramírez   R. de Hoz   A. Triviño

Abstract Details


To compare variations in surface morphology, as studied by scanning electron microscopy (SEM), of explanted intraocular lenses (IOLs) concerning the cause leading to the explantation surgery.


Vissum Corporation, Alicante, Spain


Prospective multicentre study. Explanted IOLs were analyzed by SEM and energy-dispersive X-ray spectroscopy. The IOLs were explanted in the centres of the research group from 2006 to 2012. The primary procedure was phacoemulsification in all cases.


The study evaluated 40 IOLs. The main causes for explantation were IOL dislocation, refractive error and IOL opacification. Those, explanted due to dislocation, demonstrated calcifications in 8 lenses (50%), salt precipitates in 6 cases (37.5%), and erythrocytes and fibrosis/fibroblasts in 2 cases (12.5%). In the refractive error cases, the SEM showed proteins in 5 cases (45.5%) and salt precipitates in 4 lenses (36.4%). In IOL opacification, the findings were calcifications in 2 of the 3 lenses (66.6%) and proteins in 2 lenses (66.6%).


A marked variation in surface changes were observed by SEM. Findings did not correlate with cause for explantation. SEM is a useful tool that provides exclusive information regarding the IOL biotolerance and its interactions with the surrounding tissues.

Financial Interest:


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