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Biometric parameters of a full-eye length SS-OCT-scan biometer prototype compared with optical biometry based on partial coherence interferometry (PCI) and optical low coherence reflectometry (OLCR)

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Session Details

Session Title: Cat Surgery Equipment/inst/OVD

Session Date/Time: Tuesday 16/09/2014 | 16:30-18:00

Paper Time: 16:42

Venue: Boulevard B

First Author: : K.Kunert GERMANY

Co Author(s): :    M. Blum   W. Haigis   W. Sekundo        

Abstract Details

Purpose:

To compare biometic parameters of a full-eye length SS-OCT-scan biometer prototype with optical biometry based on partial coherence interferometry (PCI) and optical low coherence reflectometry (OLCR).

Setting:

Comparative multicenter clinical study: Department of Ophthalmology, Helios Clinic Erfurt, Germany; Department of Ophthalmology, University of Wuerzburg, Germany; Department of Ophthalmology, Philipps University of Marburg, Germany

Methods:

One eye was randomly selected from a total of 84 cataract patients participating in the study. Biometry was taken with three different biometers: full-eye length SS-OCT-scan biometer prototype IOLMaster 700 (Carl Zeiss Meditec AG, Jena, Germany) – partial coherence interferometry (PCI) based biometry IOLMaster 500 (Carl Zeiss Meditec AG, Jena, Germany) – optical low coherence reflectometry (OLCR) based biometry Lenstar 900 (Haag Streit, Köniz, Switzerland). For the full-eye length SS-OCT-scan biometer, five measurements were captured for each patient while one reference measurement was captured with PCI based and OLCR based biometry respectively. Axial length (AL) and anterior chamber depth (ACD) were compared between the first measurement of SS-OCT-scan biometer and PCI device. Central corneal thickness (CCT) and lens thickness (LT) were compared between the first measurement of SS-OCT-scan biometer and OLCR device. Repeatability performance of SS-OCT-scan biometer was evaluated based on the five measurements captured for each patient. Eight eyes were excluded due to missing data. This leaves 76 eyes for device comparison and evaluation of repeatability performance of the SS-OCT-scan biometer prototype.

Results:

Mean and mean standard deviation of full-eye length SS-OCT-scan biometry for CCT, ACD, LT and AL was 549 ±2,1µm, 3,09mm ±8,0µm, 4,49mm ±5,7µm and 23,42mm ±5,9µm, respectively. Mean difference and limits of agreement between SS-OCT-scan biometry and PCI biometry for AL was +1,9 µm ranging from -42,9µm to +46,8µm and for ACD -47,6µm ranging from -0,46mm to +0,36mm. Mean difference and limits of agreement between SS-OCT-scan biometry and OLCR biometry for CCT was -1,5µm ranging from -10,5µm to +7,5µm and for LT +14,4µm ranging from -0,16mm to +0,19mm.

Conclusions:

Full-eye-length SS-OCT-scan biometry showed high success rate and repeatability performance for all biometric parameters. Agreement of AL and ACD between PCI biometry and SS-OCT-scan biometry was excellent. So was the agreement of CCT and LT between SS-OCT-scan biometry and OLCR biometry. Limits of agreement for AL and CCT were well below clinical relevance. While clinical relevance of ACD and LT parameters does not apply to all IOL calculation approaches, some device variation occurred notably for ACD and LT measurements as shown by the limits of agreement. It remains to be validated if high repeatability shown by SS-OCT-scan biometry will result in better post-operative outcomes for those 4th generation approaches making use of ACD and LT parameters.

Financial Interest:

One or more of the authors... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, One or more of the authors... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One or more of the authors... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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