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Trans-epithelial photorefractive keratectomy with adjunctive Mitomycin C for the correction of residual myopia after LASIK

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Session Details

Session Title: Surface Ablations for Correction of Ammetropias

Session Date/Time: Tuesday 16/09/2014 | 08:00-10:30

Paper Time: 10:06

Venue: Auditorium

First Author: : W.Ghobashy EGYPT

Co Author(s): :    A. Abd El Ghany              

Abstract Details


To evaluate the efficacy and safety of Trans- epithelial photorefractive keratectomy with adjunctive Mitomycin-C over LASIK flaps for the treatment of residual myopia following LASIK.


AlGhawhara Eye Center, Ismailia, Egypt


In this single center, retrospective clinical study, 12 eyes of 9 patients (mean age 32.67 ± 2.8 years) who had Mitomycin-C (MMC) (0.02%, 20 seconds) during Trans-PRK for the treatment of residual myopic error with a mean spherical equivalent (-1.00 ±0.69 Diopter) following myopic LASIK were evaluated. The retreatment procedures were performed after an average 13.67 ± 1.15 months of primary LASIK with Schwind Amaris 500E excimer laser, with Trans PRK plate form. All patients underwent slit-lamp microscopy, manifest and cycloplegic refraction, Sirus 3D corneal analysis, merging Scheimpflug technology, with Placido topography, pachymetry, pupillometry, and wavefront analysis pre- and postoperatively. All patients underwent follow-up at 1 day, 1 week, and 1, 3, and 6 months.


Mean time between LASIK and Trans-PRK retreatment was 13.67 months (range: 13 to 15 months). No intra- or postoperative complications occurred during primary LASIK or Trans -PRK retreatment. Mean spherical equivalent refraction of attempted correction with Trans PRK was -1.00 ±0.69 Diopter. By the end of 6th postoperative month, the average uncorrected visual acuity (UCVA) improved from 0.48 (range: 0.15 to 0.7) to 0.8 (range: 0.3 to 1.0). All eyes showed improvement in UCVA. Four eyes had subjective improvement of glare symptoms, none of the eyes in the cohort developed postoperative haze, or any complications.


Trans-epithelial photorefractive keratectomy with adjunctive Mitomycin-C is a safe and effective option for correction of residual myopia following LASIK.

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