London 2014 Registration Visa Letters Programme Satellite Meetings Glaucoma Day 2014 Exhibition Hotel Booking Virtual Exhibition Star Alliance
london escrs

Course handouts are now available
Click here

Come to London


WATCH to find out why

Site updates:

Programme Updates. Programme Overview and - Video Symposium on Challenging Cases now available.

Amniotic membrane transplantation in failed trabeculectomy

Search Abstracts by author or title
(results will display both Free Papers & Poster)

Session Details

Session Title: Glaucoma II

Session Date/Time: Monday 15/09/2014 | 08:00-10:30

Paper Time: 10:16

Venue: Boulevard F (Level 1)

First Author: : V.Sarnicola ITALY

Co Author(s): :    M. Chiara   P. Toro Ibanez   C. Sarnicola   E. Sarnicola   A. Ruggiero  

Abstract Details


To determine the efficacy and safety of amniotic membrane transplantation for trabeculectomy in patients with previous failed filtering blebs.


Misericordia Hospital, Grosseto, Italy


A consecutive series of 19 eyes from 18 patients with one or more failed trabeculectomies were enrolled in this retrospective study. Trabeculectomy, with amniotic membrane positioned as a 'graft' under the scleral flap, was performed, and the intraocular pressure (IOP), number of anti-glaucoma medications, appearance of the filtering bleb, and intra- and postoperative complication data were retrospectively analyzed for a period of 24 months. Success was defined as IOP <21 mm Hg at the end of the follow-up period.


The median preoperative pressure was 29mm Hg (IQR=5 mm Hg), with an average of 2.8 glaucoma medications (range 1-4). At 6 months postoperative the median IOP was 18mm Hg (IQR=1.75 mm Hg) with no further significant increases recorded, settling at 19mm Hg (IQR=3.25 mm Hg) at the end of the 24-month follow-up. Success was achieved in all 19 cases (100%). Only one patient (5%) required postoperative anti-glaucoma therapy to reach the target pressure. At 24 months after surgery, 18 of 19 (95%) amniotic membrane filtering blebs were functioning well without anti-glaucoma therapy. No patients had severe intra- or postoperative complications.


Amniotic membrane transplantation in trabeculectomy seems to be a safe and useful procedure for improving the surgical outcome and maintaining low postoperative IOP in patients with a high risk of surgical failure.

Financial Interest:


Back to previous