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Postmortem ultra-structural analysis of a cornea transplanted with Descemet's membrane endothelial keratoplasty (DMEK)

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Session Details

Session Title: Cornea Surgical I

Session Date/Time: Monday 15/09/2014 | 08:00-10:30

Paper Time: 09:45

Venue: Boulevard B

First Author: : E.Livny THE NETHERLANDS

Co Author(s): :    J. Parker   M. van der Kaaij   E. Haasdijk   J. van der Wees   M. Bruinsma   G. Melles

Abstract Details


To describe the ultra-structure of the host-donor interface in the eye of a recently deceased patient, having previously undergone Descemet Membrane Endothelial Keratoplasty (DMEK).


Netherlands Institute for Innovative Ocular Surgery / Tertiary referral center.


The eye was enucleated post-mortem and after standard decontamination, the corneo-scleral button was excised, cut into 4 quadrants and processed for light and transmission electron microscopy (TEM) evaluation.


TEM revealed close attachment of the donor’s Descemet membrane to the host’s stroma and projection of stromal collagen fibers into the interfacial matrix, resembling a normal ’virgin’ corneal architecture.


Ultra-structurally, an attached DMEK graft closely resembles that of an un-operated, healthy eye with no appreciable adventitious or missing structures.

Financial Interest:

One or more of the authors... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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