London 2014 Registration Visa Letters Programme Satellite Meetings Glaucoma Day 2014 Exhibition Hotel Booking Virtual Exhibition Star Alliance
london escrs

Course handouts are now available
Click here

Come to London


WATCH to find out why

Site updates:

Programme Updates. Programme Overview and - Video Symposium on Challenging Cases now available.

Inflammatory cell response in capsulotomies obtained with femtosecond laser-assisted cataract surgery

Search Abstracts by author or title
(results will display both Free Papers & Poster)

Session Details

Session Title: Femtocataract I

Session Date/Time: Sunday 14/09/2014 | 08:00-10:00

Paper Time: 09:03

Venue: Boulevard A

First Author: : L.Mastropasqua ITALY

Co Author(s): :    R. Calienno   L. Toto   C. Curcio   P. Mattei   A. Mastropasqua   G. Falconio

Abstract Details


to compare inflammatory cell response of capsulotomies specimens obtained with femtosecond laser–assisted cataract surgery and manual continuous curvilinear capsulorhexis.


Ophthalmology Clinic, University 'G. d'Annunzio'Chieti-Pescara


Seventy capsulorhexes obtained using a conventional manual technique and femtosecond laser with different energy settings were divided into 5 groups as follows: Group 1 (14 capsulorhexes) obtained with the manual technique, Groups 2 (14 capsulorhexes) obtained with the femtosecond laser at 6.0 μJ, Group 3 (14 capsulorhexes) at 7 μJ, Group 4 (14 capsulorhexes) at 10.0 μJ and Group 5 (14 capsulorhexes) at 13.0 μJ. After treatment capsulorhexes were prepared for immunohistochemistry evaluation. The expression of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) was investigated in all samples.


Immunohistochemical staining showed very few NF-κB positive cells in samples of manual technique compared to total number of cells. The percentage of NF-κB positive cells was significantly increased in samples treated with femtosecond laser at 13 µj with respect to manual technique (p=0.0005).


Inflammatory cell response of capsulorhexes was related to laser pulse energy and was comparable to manual capsulorhexis for low energy settings.

Financial Interest:


Back to previous