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Contrast sensitivity function in light adjustable lens patients with extended depth of focus

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Session Details

Session Title: IOL Technology / Accommodative IOLs etc.

Session Date/Time: Saturday 13/09/2014 | 16:00-18:00

Paper Time: 16:42

Venue: Boulevard A

First Author: : E.Villegas SPAIN

Co Author(s): :    L. Hervella   J. Caballero   J. Marin   P. Artal     

Abstract Details


To evaluate the contrast sensitivity function (CSF) in patients implanted bilaterally with light adjustable intraocular lenses (LALs), with one eye set to emmetropia and the other with induced spherical aberration to increase the depth of focus.


Laboratorio de Optica, Universidad de Murcia, Murcia, Spain 1) Servicio de OftalmologĂ­a, Hospital Virgen de la Arrixaca, Murcia, Spain 2)


Twenty cataract patients were implanted bilaterally with LALs (Calhoun Vision, Pasadena, USA). Two weeks after surgery, the implanted lenses were irradiated with appropriate spatial light intensity profiles to correct defocus and astigmatism in both eyes and to induce a pre-defined amount of negative spherical aberration (SA) in the non-dominant eye. After the adjustment procedures, two photo-lockin treatments were performed to ensure the LALs were fixed. A wavefont sensor was used to control refraction and spherical aberration during the entire adjustment process. Visual acuity (VA) and CSF were measured using a computer-assisted procedure both monocularly (each eye separately) and binocularly. A Bayesian adaptive method was used to measure the CSF accurately with duration of the test acceptable for IOL patients (Lesmes et al., J. Vision, 10, 1, 2010).


The eyes set to emmetropia had values of uncorrected distance VA higher than 1.0 (decimal). In the eyes with aspheric treatments, the final negative SA ranged between -0.05 and -0.23 microns (for a 4-mm pupil). As expected, VA decreased for distance and increased for near with larger magnitudes of induced SA. Mean values of binocular uncorrected VA was around 1.00 at far and intermediate (60 cm) distances. VA at 40 cm was 1.00 and 0.80 in eyes with SA magnitude higher and smaller than 0.1 microns respectively. Uncorrected monocular contrast sensitivity was better in the emmetropic eyes than in aspheric eyes at all spatial frequency. Binocular CSFs were similar to those found in the dominant (emmetropic) eye.


The bilateral implantation of LALs, followed with the proper light treatments to correct refractive errors and to induce negative spherical aberration in the non-dominant eye to increase the depth of focus, provided excellent visual acuity without a significant reduction of the binocular contrast sensitivity.

Financial Interest:

One or more of the authors... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, One or more of the authors... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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