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Evaluation of the ActaLens silicone accommodating intraocular lens: results of initial safety and efficacy study

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Session Details

Session Title: IOL Technology / Accommodative IOLs etc.

Session Date/Time: Saturday 13/09/2014 | 16:00-18:00

Paper Time: 16:22

Venue: Boulevard A

First Author: : J.Vicencio PHILIPPINES

Co Author(s): :    R. Henson   A. Angeles   A. Phillips        

Abstract Details

Purpose:

To make an initial assessment of the safety and efficacy of the ActaLens silicone accommodating intra-ocular lens and describe its translational movement via ultrasound biomicroscopy (UBM) and scheimpflug photo analysis

Setting:

Clinica Henson Eye, Ear, Nose and Throat Center, Angeles City, Philippines

Methods:

A prospective case series of eight consecutive patients with bilateral cataracts underwent phacoemulsification with “in the bag” implantation of the ActaLens (Emmetrope, Los Angeles, CA) silicone intraocular lens. Contralateral eyes were randomized to receive either Acrysof IQ monofocal (Alcon) or CrystaLens AO accommodating (B&L) lenses. All implantations were made through a sutureless corneal incision. There were no peri-operative or post-operative complications in any of the 16 eyes. After the 6th week and the 4th month, translational movement (displacement of the lens forward with accommodation) by pharmacological means (pilocarpine drop) was measured via ultrasound biomicroscopy (Reflex UBM, Reichert) and scheimpflug (Oculus Pentacam HR) studies for all 16 eyes.

Results:

All eight patients who received ActaLens implants showed significant forward movement of the IOL from a resting to an accommodated state following application of topical pilocarpine drops. Six weeks after surgery, the average forward movement, as measured by UBM, for the ActaLens was 0.23mm + .06 (0.17mm to 0.33 mm). For the CrystaLens AO and Acrysof IQ, the measurements were -.05 mm + .02 ( -.07 mm to -.04 mm) and -.04 mm + .18 ( -.29 mm to .11 mm) respectively. All eight ActaLens patients likewise exhibited backward movement to resting levels after disaccommodation. Similar findings were also seen with serial scheimpflug photos in all eight ActaLens patients.

Conclusions:

The ActaLens silicone accommodating IOL demonstrated good safety in this study. Moreover, it is effective in producing significant forward translational movement via pharmacologically induced accommodation based on UBM and scheimpflug imaging studies.

Financial Interest:

One or more of the authors... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One or more of the authors... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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