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Unusual opacification of hydrophobic IOLs

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Session Details

Session Title: IOL technology/New IOLs etc.

Session Date/Time: Saturday 13/09/2014 | 08:30-10:30

Paper Time: 09:28

Venue: Boulevard A

First Author: : J.Novak CZECH REPUBLIC

Co Author(s): :                  

Abstract Details


In 2005 we have implanted group of IOL Matrix401 from Medennium. Its unique property was relative high diffuse opacity of {mean±SD, 8.63±2,29}% (measured by Pentacam) one year after surgery. In that time we have considered and reported this phenomenon to be profitable because a regular acrylic IOL has very low opacity of around 5% compared with lens crystallina and causes glare of retina after lens exchange. Eight years after implantation we have repeat the same examination.


Department of Ophthalmology, Regional Hospital and University Pardubice


Ten eyes with IOL Matrix401 after cataract surgery were examined by Pentacam HR from Oculus. The examination was performed in dark conditions if pupil diameter reached more than 6mm. Measurement of relative IOL opacity was performed in 4 squares 1mm from central point of IOL in the material of IOL (in the sections of 90o and 180o). Comparative level of the IOL opacity was measured in 4 squares 0,5mm above IOL surface and 1mm from the IOL axis in the aqueous space of the anterior chamber (the same sections of 90o and 180o). There is methodical problem to measure influence of higher IOL opacity on visual acuity and contrast senzitivity compared with original level immediately after surgery (opacification of posterior capsule and potential age related changes of macula).


Comparative level of opacity in the aqueous space was established {mean±SD, 4.22±0.22}%. The highest level of IOL opacity was 22,1%, average in all 10 measured IOLs Matrix was 17.11±3.67%. No glistenings were registered. Decrease of VA related on IOL opacification was determined only in 2 eyes (loss of 1line), in all was the significant decrease in contrast sensitivity (CSV1000) in comparison with normal level of corresponding age. There was no clinical indication for IOL explantation.


Hydrophobic IOL Matrix401 has no optical stability in time. The IOL opacity reaches the level of significant cataract after its persitence of 8 years in the eye. Increase of IOL opacity in time is not only in the superficial level of substance such as originates in the well known hydrophobic IOL Acrysof from Alcon, but uniform in all space of IOL. There is the question of next increase of IOL opacity because the cause of this phenomenon cannot be studied without IOL explantation. Hydrophobic acrylic raw materials are not so safe in relation to hydrophilic acrylates as we believed after AquaSense scandal.

Financial Interest:

One or more of the authors... travel has been funded, fully or partially, by a competing company

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