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Localized opacification of hydrophilic acrylic intraocular lenses after procedures using intracameral injection of air/gas

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Session Details

Session Title: IOL technology/New IOLs etc.

Session Date/Time: Saturday 13/09/2014 | 08:30-10:30

Paper Time: 09:22

Venue: Boulevard A

First Author: : L.Werner USA

Co Author(s): :    G. Wilbanks   C. Nieuwendaal   A. Dhital   A. Waite   G. Schmidinger   W. Lee

Abstract Details


To describe clinicopathological findings in a series of cases of intraocular lens (IOL) opacification after procedures involving intracameral injections of air/gas.


John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.


Seven hydrophilic acrylic IOLs were explanted after Descemet-stripping endothelial keratoplasty/Descemet-stripping automated endothelial keratoplasty (DSEK/DSAEK) because of a localized central optic opacification associated with significant decrease in visual acuity and complaints of foggy vision. The lenses underwent pathological and histochemical evaluation. Light scattering measurements were also performed on the surface of one of the explants.


The 7 explanted lenses were represented by 6 different hydrophilic acrylic designs, from 5 manufacturers. Gross and light microscopy showed that granular deposits were densely distributed in an overall round pattern within the margins of the capsulorhexis or the pupil, on the anterior surface/subsurface of the IOLs. The granules stained positive for calcium (alizarin red and von Kossa method). Light scattering on the anterior optic surface was very high (228 CCT versus 13 CCT on a control lens).


We describe a localized pattern of calcification on the anterior surface/subsurface of various hydrophilic acrylic IOLs. Surgeons should be aware of this phenomenon following DSEK/DSAEK procedures in pseudophakic patients with hydrophilic acrylic lenses.

Financial Interest:


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