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Laboratory analysis of different implant options for highly hyperopic/nanophthalmic eyes

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Session Details

Session Title: IOL technology/New IOLs etc.

Session Date/Time: Saturday 13/09/2014 | 08:30-10:30

Paper Time: 09:10

Venue: Boulevard A

First Author: : B.Trindade BRAZIL

Co Author(s): :    F. Amaral   D. Monteiro           

Abstract Details


To evaluate the optical performance of different possibilities of implants in a high hyperopic eye


OptMA LAb - Federal University of Minas Gerais


IOL models were designed and optimized in an optical design software (Radiant Zemax® v13.0. LLC, Redmond, WA) using a modified Liou and Brennan eye model. Four different IOL powers were created: 20, 30, 40 and 60D lens. All the lenses were aspheric and optimized to have spherical aberration equal to zero. 65 different modified Liou and Brennan eye models with dimensions comparable to nanophthalmic eyes were used for testing 3 different implant options. Option 1: a single 60D IOL. Option 2: two 30D lenses. Option 3: a 20D IOL (anteriorly) and a 40D lens (posteriorly). A 3 and 5mm pupils were used. The area under modulation transfer function (MTF) curve was calculated and spherical aberration was recorded for analysis.


MTF analysis shows that the single aspheric high-power IOL had the closest curve to the diffraction limit of the eye. For the 3mm pupil, the median area under the MTF curve as a percentage of the diffraction limit was 90.033 (95%CI 87.584 - 92.180) for implant option 1, 78.707 (95%CI 76.108 - 80.842) for option 2 and 80.340 (95% CI 77.795 - 82.705) for option 3. Spherical aberration for the 3mm pupil was 0.062µm (95% CI 0.055µm - 0.070µm) for option 1, 0.093µm (95% CI 0.087µm - 0.099µm) for option 2 and 0.089µm (95% CI 0.082µm - 0.095µm) for option 3. Statistical analysis showed a significant difference between the single IOL and the piggyback options (p<0.001) however both piggyback options were statistically equivalent in the analyzed variables (p>0.05).


The computer simulation showed that one single high-power aspheric IOL had a better optical performance than piggybacking lower-power aspheric IOLs. MTF analysis revealed that a single high-power lens provides higher contrast sensitivity when compared to the piggyback options.

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