Lisbon 2017 Delegate Registration Programme Exhibition Virtual Exhibition Satellites OneWorld Travel Discount
escrs app advert


Search Title by author or title

Controversies in the diagnosis and management of central toxic keratopathy (CTK)

Poster Details

First Author: M.Samuel UK

Co Author(s):                        

Abstract Details


Central Toxic Keratopathy still remains a less understood condition making the diagnosis and management difficult. It has been described as a non inflammatory interface complication after LASIK which despite similarities to grade 4 DLK has been described as a separate entity. It has also been described that the condition is self-limiting and does not respond topical steroids or surgical intervention.The purpose of our study is to prove that the condition is not a separate entity but an early onset Grade 4 DLK and that it responds to surgical intervention with a flap lift combined with intensive topical steroids




It was a retrospective study. Notes were reviewed.Three cases had bilateral Femtosecond LASIK.One case presented with DLK in the left eye on first day which progressed to G4 DLK in 3 days. The patient was treated with topical steroids and improved gradually over next 4 months.The other two cases developed bilateral DLK on first day. This progressed very rapidly to grade 4 on the second day with corneal haze and stria. The case was treated with flap wash out and intensive steroids with quick improvement of symptoms in 3 days and improvement in visual recovery within 3 months.


It was a retrospective study based on review of surgical notes of three patients who presented with DLK which rapidly progressed to Grade 4 DLK and a tentative diagnosis of CTK was made.One case was treated with intensive topical steroids and improved gradually over next 4 months.Two cases were treated surgically by flap lift a and interface washout and these two cases showed rapid improvement in symptoms in 2 to 5 days and complete visual rehabilitation in 3 to 4 months of the surgical intervention


We propose CTK is not a separate entity but a variant of Grade 4 DLK or early onset Grade 4 DLK when the inflammation progresses from Grade 1 to Grade 4 DLK in a matter of couple of days.We propose surgical intervention with flap washout accompanies by intensive steroids results in quick improvement of symptoms and complete visual recovery in a matter of weeks

Financial Disclosure:


Back to Poster listing