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Clinical validation of the VAO adaptive optics visual simulator

Poster Details

First Author: L.Hervella Ginesta SPAIN

Co Author(s):    E. Villegas   J. Marin   P. Artal              

Abstract Details


To validate in the clinic the Adaptive Optics Visual Simulator VAO (Voptica SL, Murcia, Spain) for fast and accurate refraction estimates.


Laboratory of Clinical Optics, University of Murcia, Spain.


VAO combines optical measurements and visual testing within the same compact instrument. It incorporates a Hartmann-Shack wave-front sensor to measure objective refraction and aberrations, together with a spatial light modulator capable of correcting or inducing any optical profile while performing visual testing. In seventy-four eyes of 37 subjects, subjective refraction (SR) was measured using VAO. The agreement of spherical equivalent (M) and cross cylinders (J0 and J45) with a standard refraction technique was estimated using different statistic parameters: 95% confidence limits (CL), Student�Â�´s t- test or Wilcoxon Rank Sum and Pearson correlation coefficient(r).


There is a high correlation between the elements of SR (M, J0 and J45) measured with VAO and the standard technique (r�â�‰�¥0.92) and the differences are not significant different (p>0.05). The 95% CL of M, J0 and J45 were �Â�±0.38, �Â�±0.07 and �Â�±0.07 D respectively. The reproducibility of SR measurements between two examiners had an excellent correlation (r�â�‰�¥0.93) and there were not significant differences between them (p>0.05). The 95% CL of M, J0 and J45 were �Â�±0.29, �Â�±0.08 and �Â�±0.07 D respectively.


Refraction results using the VAO adaptive optics visual simulator were in agreement with those obtained in a standard technique while offering significant advantages in terms of time and clinic space. VAO is a new instrument that offers significant advantages in the optical and visual assessment of cataract and refractive surgery patients.

Financial Disclosure:

research is funded, fully or partially, by a competing company

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