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Predicted visual performance of different IOL technologies: effect of including multiple spatial frequencies

Poster Details

First Author: A.Alarcon THE NETHERLANDS

Co Author(s):    C. Canovas   H. Weeber   R. Rosen   D. Chang   P. Piers        

Abstract Details


Through focus visual acuity (VA) is measured clinically using optotypes which contain a wide range of spatial frequencies. All these frequencies play a role in recognizing the optotypes. Therefore, it is expected that multiple spatial frequencies need to be considered to find a good correlation between clinical VA and optical bench data. This study makes use of data from several different intraocular lens (IOL) technologies. The visual performance at different spatial frequencies is compared to simulated VA.


AMO Groningen B.V., Groningen, Netherlands


Through-focus modulation transfer function (MTF) and phase transfer function (PTF) were measured for an extended range of vision IOL (ERV), a bifocal, a trifocal, and a quadrifocal IOL. Measurements were performed in white light for a 3 mm pupil. Binocular VA was simulated using the area under the MTF from 1 to 50 cycles per mm (MTFa).


Simulated VA from -0.5D to -2.0D was better correlated with the lower spatial frequencies than for higher spatial frequencies (R2=0.41, 0.56 and 0.70 for 50, 40 and 20 cycles per mm respectively). For the lower spatial frequencies, the ERV IOL showed a monotonic change in MTF while trifocal and quadrifocal IOLs showed a bimodal MTF similar to that of the bifocal IOL. Simulated VA predicted a range of vision better than 0.0 logMAR from 0 to -1.5D for the ERV design. On average the ERV design provided an improvement in intermediate VA of 0.10 logMAR respect to the multifocal IOLs.


Through focus MTF have a spatially frequency dependent performance for the four different IOL designs. Among the spatial frequencies, the lower ones are better correlated with simulated VA. Results show that it is essential to include multiple spatial frequencies in order to provide a good prediction of the performance of an IOL.

Financial Disclosure:

is employed by a for-profit company with an interest in the subject of the presentation, receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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